They are used in the production process of solid pharmaceutical forms in the granulation stage. During granulation, the conversion of small particles into larger granules or even small-sized tablets is achieved.

The size of the particles is a basic condition for the creation of a homogeneous mixture during the mixing process of the different materials used for the production of a pharmaceutical product. They are still used today and are basic equipment for production units of solid pharmaceutical products such as tablets and capsules. 

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